November 4, 2025
25-119
Jessica Pope
Communications and Media Relations Coordinator
11月21日，美高梅博彩caf<s:1> Scientifique专注于癌症药物开发
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| 托马斯·曼宁博士，美高梅博彩的化学教授 |
编者注：由于不可预见的情况，该活动已从11月14日改为11月21日。
VALDOSTA — The 科学与数学学院 at 美高梅博彩 will present Café Scientifique from 5:30 p.m. to 6:30 p.m. Friday, Nov. 21, at Augie’s Cafe. 这个活动对公众开放。
Dr. Thomas Manning, professor of chemistry, will discuss “Copper and Cancer: Why Do They Go Hand in Hand?” Cancer drug development researchers are exploring copper in two main ways — using copper to selectively kill cancer cells (through cuproptosis, copper-based nanoparticles, or combination therapies) and targeting the copper-binding proteins that protect cancer cells.
“Copper, at low levels, is an essential nutrient in healthy people,” Manning shared. “At higher levels, it can have different levels of toxicity. 对于癌细胞来说，它们不仅含有更高水平的铜，而且铜是癌细胞所需的一种必需营养素。 In our novel, small molecule-copper drugs for cancer, drug resistant tuberculosis, and pox viruses, we have demonstrated a unique method to use copper as a delivery method at the molecular level to increase the efficacy of medications and, in some cases, to overcome resistance.”
Manning said his student research team has had “35 novel compounds enter pre-clinical trials against cancer cell lines and more than a dozen complexes tested against pox viruses and drug-resistant tuberculosis.”
Café Scientifique is a global forum for debating science issues and allowing attendees the opportunity to ask questions. 在世界各地，它是一个任何人都可以来探索最新科技理念的地方。 会议在咖啡馆、酒吧、餐馆和其他社区地点举行。 The only request is that attendees purchase a beverage or food item — even if it’s just a cup of coffee — from the host venue.
“This event is an opportunity for anyone, from any background and level of education, to learn more about science,” said Dr. Cristina Calestani, professor of biology, interim associate dean of the 科学与数学学院, and event organizer. “It is not meant to be a lecture. 对于公众，以及我们vs上的学生和同事来说，这是一个以他们可以理解的格式提出问题并获得答案的机会。 The informal setting facilitates the interaction between the scientist and the public.”
Augie’s Cafe is located at 1811 Jerry Jones Drive in Valdosta.
在网上：www.mgmbetbc.com/cosm/
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